I've never picked up a hitchhiker, but last year I did something that, if my dd had done this, I would have been furious with her -- I accepted a ride from a stranger.
After the tornadoes roared through Alabama last April and knocked out the power to the entire northern part of the state, I heard that Publix was open with generator power, so I walked what would have been a 4 mile trip there to get some emergency supplies (I had 1/2 tank of gas in my car and dh had 3/4 of a tank, but there was no power, no one could pump gas, so dh and I decided to only drive in a serious emergency). On the way back home with my heavy bag, a guy stopped and offered me a ride. I hesitated, but I decided to chance it. He turned out to be a very nice guy. People were stepping up and doing out-of-the-ordinary things in an out-of-the-ordinary situation, so I appreciated the ride. Under normal circumstances, I would never accept a ride from a stranger.